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Author  |
Cottet, K.; Genta-Jouve, G.; Fromentin, Y.; Odonne, G.; Duplais, C.; Laprévote, O.; Michel, S.; Lallemand, M.-C. |
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Title |
Comparative LC-MS-based metabolite profiling of the ancient tropical rainforest tree Symphonia globulifera |
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Journal Article |
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Year |
2014 |
Publication |
Phytochemistry |
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Phytochemistry |
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108 |
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102-108 |
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Keywords |
Kendrick mass defect; Lc-Ms; Plant organs; Symphonia globulifera; Untargeted metabolomics; Symphonia globulifera |
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Abstract |
In the last few years, several phytochemical studies have been undertaken on the tropical tree Symphonia globulifera leading to the isolation and characterisation of several compounds exhibiting antiparasitic activities against Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani. The comparative LC-MS based metabolite profiling study conducted on the tree led to the identification of compounds originating from specific tissues. The results showed that renewable organs/tissues can be used as the starting material for the production of polycyclic poly-prenylated-acylphloroglucinols, therefore reducing impacts on biodiversity. This study also underlined the lack of knowledge on the secondary metabolites produced by S. globulifera since only a small number of the total detected features were putatively identified using the database of known compounds for the species. |
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Address |
Laboratoire de Chimie et Toxicologie Analytique et Cellulaire, UMR 8638, Université Paris Descartes Sorbonne Paris Cité, 4 Avenue de l'ObservatoireParis, France |
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Elsevier Ltd |
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00319422 (Issn) |
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Notes |
Export Date: 2 December 2014; Coden: Pytca; Correspondence Address: Genta-Jouve, G.; Laboratoire de Pharmacognosie, UMR 8638, Université Paris Descartes Sorbonne Paris Cité, 4 Avenue de l'Observatoire, France |
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EcoFoG @ webmaster @ |
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569 |
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