| Record |
Author  |
Cachet, N.; Ho-A-Kwie, F.; Rivaud, M.; Houel, E.; Deharo, E.; Bourdy, G.; Jullian, V. |
| Title |
Picrasin K, a new quassinoid from Quassia amara L. (Simaroubaceae) |
Type |
Journal Article |
| Year |
2012 |
Publication |
Phytochemistry Letters |
Abbreviated Journal |
Phytochem. Lett. |
| Volume |
5 |
Issue |
1 |
Pages |
162-164 |
| Keywords |
Malaria; P. falciparum; Quassia amara; Quassinoids; Simaroubaceae |
| Abstract |
A new quassinoid Picrasin K 1 was isolated from a decoction made of Quassia amara leaves, traditionally used in French Guyana to treat malaria. The structure and relative stereochemistry of 1 was determined through extensive NMR analysis. Picrasin K showed a low activity against Plasmodium falciparum in vitro (IC 50 = 8 μM), and a similar low activity on human cancerous cells line (IC 50 = 7 μM on MCF-7 cells line). © 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. |
| Address |
CNRS, UMR Ecofog, Université des Antilles et de la Guyane, Cayenne, France |
| Corporate Author |
|
Thesis |
|
| Publisher |
|
Place of Publication |
|
Editor |
|
| Language |
|
Summary Language |
|
Original Title |
|
| Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
| Series Volume |
|
Series Issue |
|
Edition |
|
| ISSN |
18743900 (Issn) |
ISBN |
|
Medium |
|
| Area |
|
Expedition |
|
Conference |
|
| Notes |
Export Date: 8 March 2012; Source: Scopus; doi: 10.1016/j.phytol.2011.12.001; Language of Original Document: English; Correspondence Address: Jullian, V.; UMR-152 Pharma-Dev, IRD, Université Paul Sabatier Toulouse 3, 31062 Toulouse, France; email: jullian@cict.fr |
Approved |
no |
| Call Number |
EcoFoG @ webmaster @ |
Serial |
382 |
| Permanent link to this record |
