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| Author | Laurans, M.; Martin, O.; Nicolini, E.; Vincent, G. | ||||
| Title | Functional traits and their plasticity predict tropical trees regeneration niche even among species with intermediate light requirements | Type | Journal Article | ||
| Year | 2012 | Publication | Journal of Ecology | Abbreviated Journal  |
J. Ecol. |
| Volume | 100 | Issue | 6 | Pages | 1440-1452 |
| Keywords | Canopy disturbance; Determinants of plant community diversity and structure; Growth rate; Irradiance; Leaf life span; Leaf mass per area; Niche differentiation; Phenotypic plasticity; Shade tolerance; Tropical moist forest | ||||
| Abstract | Niche differentiation is a key issue in the current debate on community assembly mechanisms. In highly diverse moist tropical forests, tree species sensitivity to canopy openness is thought to be a major axis in niche differentiation. In the past, the syndrome of traits driving the demographic trade-off involved in the niche-based theory of coexistence has always been established among species situated at the two extremities of the shade-tolerance gradient, even though most tropical tree species have intermediate light requirements. In addition, trait plasticity has seldom been linked to tropical tree species distribution along environmental gradients. This article examines covariations between leaf traits, whole-plant traits and niche parameters among 14 tree species with intermediate light requirements in French Guiana and across a range of canopy openness. Each functional trait measured under field conditions was characterized by a median value and a degree of plasticity expressed under contrasting light regimes. Niche differentiation was characterized in terms of spatial light gradient. We first examined covariations between functional traits then explored to what degree the median value and plasticity in functional traits could predict light niche characteristics at the sapling stage and the ontogenetic change in light availability estimated by adult stature. Leaf mass per area (LMA) was positively correlated with leaf life span (LLS); species with higher LMA and higher LLS displayed lower diameter growth rates (GRs) and lower responsiveness to canopy gap at both whole-plant and population levels. This proved that the relationships previously established over a broader range of species held true within the narrow range of the light requirements covered. Height GR plasticity accounted for 49% of the variation in light niche optimum. LMA plasticity, unlike LLS plasticity, was significantly correlated with light niche breadth and adult stature. Synthesis. This study demonstrates the relevance of considering the phenotypic plasticity in functional traits in community ecology, particularly for quantifying breadth of species distribution over environmental gradients. Our findings did not support Hubbell's hypothesis of functional equivalence and suggest that even a rather subtle variation in forest canopy disturbance promotes the coexistence of tropical tree species. © 2012 The Authors. Journal of Ecology © 2012 British Ecological Society. | ||||
| Address | UMR AMAP, IRD, TA A-51/PS2, Bd de la Lironde, France | ||||
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| Language | Summary Language | Original Title | |||
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| ISSN | 00220477 (Issn) | ISBN | Medium | ||
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| Notes | Export Date: 7 November 2012; Source: Scopus; Coden: Jecoa; doi: 10.1111/j.1365-2745.2012.02007.x; Language of Original Document: English; Correspondence Address: Laurans, M.; UMR, AMAP, CIRAD TA A-51/PS1, Bd de la Lironde, 34398 Montpellier Cedex 5, France; email: laurans@cirad.fr | Approved | no | ||
| Call Number | EcoFoG @ webmaster @ | Serial | 445 | ||
| Permanent link to this record | |||||
| Author | Fortunel, C.; Paine, C.E.T.; Fine, P.V.A.; Kraft, N.J.B.; Baraloto, C. | ||||
| Title | Environmental factors predict community functional composition in Amazonian forests | Type | Journal Article | ||
| Year | 2014 | Publication | Journal of Ecology | Abbreviated Journal |
J. Ecol. |
| Volume | 102 | Issue | 1 | Pages | 145-155 |
| Keywords | Amazonian landscape; Climatic and soil gradients; Determinants of plant community diversity and structure; Environmental filtering; Functional traits; Tree communities; Tropical forests | ||||
| Abstract | The consequences of biodiversity loss for ecosystem services largely depend on the functional identities of extirpated species. However, poor descriptions of spatial patterns of community functional composition across landscapes hamper accurate predictions, particularly in highly diverse tropical regions. Therefore, understanding how community functional composition varies across environmental gradients remains an important challenge. We sampled 15 functional traits in 800 Neotropical tree species across 13 forest plots representative of the broad climatic and soil gradients encompassed by three widespread lowland forest habitats (terra firme forests on clay-rich soils, seasonally flooded forests and white-sand forests) at opposite ends of Amazonia (Peru and French Guiana). We combined univariate and multivariate approaches to test the magnitude and predictability of environmental filtering on community leaf and wood functional composition. Directional shifts in community functional composition correlated with environmental changes across the 13 plots, with denser leaves, stems and roots in forests occurring in environments with limited water and soil-nutrient availability. Critically, these relationships allowed us to accurately predict the functional composition of 61 additional forest plots from environmental data alone. Synthesis. Environmental filtering consistently shapes the functional composition of highly diverse tropical forests at large scales across the terra firme, seasonally flooded and white-sand forests of lowland Amazonia. Environmental factors drive and allow the prediction of variation in community functional composition among habitat types in Amazonian forests. © 2013 British Ecological Society. | ||||
| Address | Department of Biology, University of Florida, Gainesville, FL, 32611, United States | ||||
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| ISSN | 00220477 (Issn) | ISBN | Medium | ||
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| Notes | Export Date: 31 December 2013; Source: Scopus; Coden: Jecoa; doi: 10.1111/1365-2745.12160; Language of Original Document: English; Correspondence Address: Fortunel, C.; INRA, UMR Ecologie des Forêts de Guyane, BP 709, Kourou Cedex, 97387, France; email: claire.fortunel@ecofog.gf; Funding Details: DEB-0743103/0743800, NSF, National Science Foundation; References: Agrawal, A.A., Fishbein, M., Plant defense syndromes (2006) Ecology, 87, pp. S132-S149; Anderson, L.O., Malhi, Y., Ladle, R.J., Aragao, L., Shimabukuro, Y., Phillips, O.L., Influence of landscape heterogeneity on spatial patterns of wood productivity, wood specific density and above ground biomass in Amazonia (2009) Biogeosciences, 6, pp. 1883-1902; Asner, G.P., Alencar, A., Drought impacts on the Amazon forest: the remote sensing perspective (2010) New Phytologist, 187, pp. 569-578; Asner, G.P., Loarie, S.R., Heyder, U., Combined effects of climate and land-use change on the future of humid tropical forests (2010) Conservation Letters, 3, pp. 395-403; Baraloto, C., Paine, C.E.T., Patiño, S., Bonal, D., Herault, B., Chave, J., Functional trait variation and sampling strategies in species-rich plant communities (2010) Functional Ecology, 24, pp. 208-216; Baraloto, C., Paine, C.E.T., Poorter, L., Beauchene, J., Bonal, D., Domenach, A.M., Hérault, B., Chave, J., Decoupled leaf and stem economics in rain forest trees (2010) Ecology Letters, 13, pp. 1338-1347; Baraloto, C., Rabaud, S., Molto, Q., Blanc, L., Fortunel, C., Hérault, B., Davila, N., Fine, P.V.A., Disentangling stand and environmental correlates of aboveground biomass in Amazonian forests (2011) Global Change Biology, 17, pp. 2677-2688; Baraloto, C., Molto, Q., Rabaud, S., Hérault, B., Valencia, R., Blanc, L., Fine, P.V.A., Thompson, J., Rapid simultaneous estimation of aboveground biomass and tree diversity across Neotropical forests: a comparison of field inventory methods (2013) Biotropica, 45, pp. 288-298; Belyea, L.R., Lancaster, J., Assembly rules within a contingent ecology (1999) Oikos, 86, pp. 402-416; Berry, S.L., Roderick, M.L., Estimating mixtures of leaf functional types using continental-scale satellite and climatic data (2002) Global Ecology and Biogeography, 11, pp. 23-39; Brando, P.M., Nepstad, D.C., Balch, J.K., Bolker, B., Christman, M.C., Coe, M., Putz, F.E., Fire-induced tree mortality in a neotropical forest: the roles of bark traits, tree size, wood density and fire behavior (2012) Global Change Biology, 18, pp. 630-641; Burnham, K.P., Anderson, D.R., Multimodel inference – understanding AIC and BIC in model selection (2004) Sociological Methods & Research, 33, pp. 261-304; Calcagno, V., de Mazancourt, C., glmulti: an R package for easy automated model selection with (generalized) linear models (2010) Journal of Statistical Software, 34, pp. 1-29; Chapin, F.S., BretHarte, M.S., Hobbie, S.E., Zhong, H.L., Plant functional types as predictors of transient responses of arctic vegetation to global change (1996) Journal of Vegetation Science, 7, pp. 347-358; Chaturvedi, R.K., Raghubanshi, A.S., Singh, J.S., Leaf attributes and tree growth in a tropical dry forest (2011) Journal of Vegetation Science, 22, pp. 917-931; Chave, J., Coomes, D., Jansen, S., Lewis, S.L., Swenson, N.G., Zanne, A.E., Towards a worldwide wood economics spectrum (2009) Ecology Letters, 12, pp. 351-366; Cingolani, A.M., Cabido, M., Gurvich, D.E., Renison, D., Diaz, S., Filtering processes in the assembly of plant communities: are species presence and abundance driven by the same traits? 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| Call Number | EcoFoG @ webmaster @ | Serial | 520 | ||
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| Author | Marcon, E.; Puech, F. | ||||
| Title | Measures of the geographic concentration of industries: improving distance-based methods | Type | Journal Article | ||
| Year | 2010 | Publication | Journal of Economic Geography | Abbreviated Journal |
J. Econ. Geogr. |
| Volume | 10 | Issue | 5 | Pages | 745-762 |
| Keywords | Geographic concentration; distance-based methods; K-density function; Ripley's K function; M function; C40; C60; R12; L60 | ||||
| Abstract | We discuss a property of distance-based measures that has not been addressed with regard to evaluating the geographic concentration of economic activities. The article focuses on the choice between a probability density function of point-pair distances or a cumulative function. We begin by introducing a new cumulative function, M, for evaluating the relative geographic concentration and the co-location of industries in a non-homogeneous spatial framework. Secondly, some rigorous comparisons are made with the leading probability density function of Duranton and Overman (2005), Kd. The merits of the simultaneous use of Kd and M is proved, underlining the complementary nature of the results they provide. | ||||
| Address | [Marcon, Eric] AgroParisTech ENGREF, UMR EcoFoG, Kourou 97310, French Guiana, Email: Florence.Puech@univ-lyon2.fr | ||||
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| Publisher | OXFORD UNIV PRESS | Place of Publication | Editor | ||
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| ISSN | 1468-2702 | ISBN | Medium | ||
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| Notes | ISI:000281183300009 | Approved | no | ||
| Call Number | EcoFoG @ eric.marcon @ | Serial | 43 | ||
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| Author | Marcon, E.; Puech, F. | ||||
| Title | Evaluating the geographic concentration of industries using distance-based methods | Type | Journal Article | ||
| Year | 2003 | Publication | Journal of Economic Geography | Abbreviated Journal |
J. Econ. Geogr. |
| Volume | 3 | Issue | 4 | Pages | 409-428 |
| Keywords | agglomeration; clustering; geographic concentration; location of firms | ||||
| Abstract | We propose new methods for evaluating the spatial distribution of firms. To assess whether firms are concentrated or dispersed, economists have traditionally used indices that analyse the heterogeneity of a spatial structure at a single geographic level. We introduce distance-based methods, Besag's L function (derived from Ripley's K function) and Diggle and Chetwynd's D function to describe simultaneously spatial distribution at different geographical scales. Our empirical applications consider the distribution of French manufacturing firms in the Paris area and in France generally. For some geographic levels, results show significant concentration or dispersion of firms according to their sector of activity. | ||||
| Address | ENGREF, Kourou 97310, French Guiana | ||||
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| Publisher | OXFORD UNIV PRESS | Place of Publication | Editor | ||
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| ISSN | 1468-2702 | ISBN | Medium | ||
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| Notes | ISI:000185742500004 | Approved | no | ||
| Call Number | EcoFoG @ eric.marcon @ | Serial | 269 | ||
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| Author | Vedel, V.; Lalague, H. | ||||
| Title | Standardized sampling protocol for spider community assessment in the Neotropical rainforest | Type | Journal Article | ||
| Year | 2013 | Publication | Journal of Entomology and Zoology Studies | Abbreviated Journal |
J. Entomol. Zool. Stud. |
| Volume | 2 | Issue | 1 | Pages | 18-34 |
| Keywords | Araneae; Biodiversity; French Guiana; Guianese Shield; Impact Assessment | ||||
| Abstract | We described, here, a standardized protocol to collect the maximum number of spiders per unit of effort from the different strata of a tropical forestry habitat. This would allow quantifying the richness of a site and would allow spatial and temporal comparisons between sites. This protocol was tested and applied in a pilot study at four sites representing three different forestry habitats of the natural reserve of La Trinité (French Guiana). Results showed every feeding guild was well represented and most of the 30 families found are represented by several individuals. Indices of species richness, number of singletons, species richness estimators from the accumulation curves and diversity and similarity indices were also calculated and all indicated that La Trinité is a rich and diverse site for spiders. The standardized protocol showed here its efficiency and its wide cover of micro-habitats and is, therefore, recommended for any impact assessment or diversity of spider study in tropical forestry environment. | ||||
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| Notes | Approved | no | |||
| Call Number | EcoFoG @ webmaster @ | Serial | 487 | ||
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| Author | Houel, E.; Bertani, S.; Bourdy, G.; Deharo, E.; Jullian, V.; Valentin, A.; Chevalley, S.; Stien, D. | ||||
| Title | Quassinoid constituents of Quassia amara L. leaf herbal tea. Impact on its antimalarial activity and cytotoxicity | Type | Journal Article | ||
| Year | 2009 | Publication | Journal of Ethnopharmacology | Abbreviated Journal |
J. Ethnopharmacol. |
| Volume | 126 | Issue | 1 | Pages | 114-118 |
| Keywords | Quassia amara L.; Simaroubaceae; Leaf tea; Antimalarial activity; Cytotoxicity; Simalikalactone D | ||||
| Abstract | Aim of the study: Our objective was to assess whether it could be contemplated to recommend Quassia amara young leaf tea for treatment against malaria. and if yes. set up a standard protocol for preparing the herbal tea. Materials and methods: The leaf tea was extracted with methylene chloride and the organic extract was fractionated with HPLC. Pure compounds were characterized and their in vitro cytotoxicity and antiplasmodial activity was determined. Results and discussion: We discovered that antimalarial Quassia amara young leaf tea contains several quassinoids: simalikalactone D (SkD. 1), picrasin B (2). picrasin H (3), neoquassin (4), quassin (5), picrasin 1(6) and picrasin J (7). These last two compounds are new. In addition. our experiments demonstrate that both biological activity and cytotoxicity of the remedy may be attributed solely to the presence of SkD. Conclusion: In conclusion, this preparation Should not be recommended for treatment of malaria until a clinical Study in humans is performed with SkD. (C) 2009 Elsevier Ireland Ltd. All rights reserved | ||||
| Address | [Stien, Didier] Univ Antilles Guyane, CNRS, UMR Ecofog, Inst Enseignement Super Guyane, F-97337 Cayenne, France, Email: didier.stien@guyane.cnrs.fr | ||||
| Corporate Author | Thesis | ||||
| Publisher | ELSEVIER IRELAND LTD | Place of Publication | Editor | ||
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0378-8741 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | ISI:000271790800015 | Approved | no | ||
| Call Number | EcoFoG @ eric.marcon @ | Serial | 94 | ||
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| Author | Odonne, G.; Bourdy, G.; Castillo, D.; Estevez, Y.; Lancha-Tangoa, A.; Alban-Castillo, J.; Deharo, E.; Rojas, R.; Stien, D.; Sauvain, M. | ||||
| Title | Ta'ta', Huayani: Perception of leishmaniasis and evaluation of medicinal plants used by the Chayahuita in Peru. Part II | Type | Journal Article | ||
| Year | 2009 | Publication | Journal of Ethnopharmacology | Abbreviated Journal |
J. Ethnopharmacol. |
| Volume | 126 | Issue | 1 | Pages | 149-158 |
| Keywords | Leishmaniasis; Medicinal plants; Traditional medicine; Chayahuita; Peru | ||||
| Abstract | Aim of the study v: A knowledge attitude and practice study centred on leishmaniasis and its treatment was performed among the Chayahuita, in Amazonian Peruvian ethnic group living in ail endemic area. This study documents traditional Chayahuita plant's use and disease concepts. Also, activity of some medicinal Plants Used by the Chayahuita is highlighted and discussed. Materials and methods: Ninety-three Chayahuita people were interviewed, following a semi-structured questionnaire focussed oil disease knowledge and perception, personal attitude and healing practices. Simultaneously, a collection of plants was performed in different ecotopes, in order to make ail extensive inventory of the pharmacopoeia. Results: For the Chayahuita, cutaneous (CL) and muco-cutaneous leishmaniasis (MCL) are considered as diseases of their own, with specific names, aetiologics, mode of transmission. Regarding CL, Chayahuita people consider that the humid characteristic of the Skill ulcer is a discriminative fact orienting the diagnostic for Ta'ta' (leishmaniasis). Forty-six different species were designated useful against LC and /or MCL (29 species by means of the questionnaire and 27 species when collecting in different ecotopes). Thirty-seven extracts corresponding to 31 Species used medicinally were screened in vitro against Leishmania amazonensis axenic amastigotes, assessing their viability by the reduction Of tetrazolium salt (MTT). Six species displayed a good activity (10 μg/ml < IC50 < 20 μg/ml): all undetermined hemi-epiphytic Clusiaceae. Cybianthus anthuriophyllus Pipoly (Myrsinaceae), two Piper, Piper sanguineispicum Trel., and Piper loretoanum Trel. (Piperaceae), Desmodium axillare Sw. DC. (Fabaceae), and Clibadium sylvestre (Aubl.) Baill (Asteraceae). Conclusion: Perception of leishmaniasis, attitude. treatments and diet prohibitions still largely reflects traditional Chayahuita cosmovision, even if some tentative of bio-medical re-interpretation is arising. (C) 2009 Elsevier Ireland Ltd. All rights reserved. | ||||
| Address | [Odonne, G.; Bourdy, G.; Estevez, Y.; Deharo, E.; Sauvain, M.] Univ Toulouse, UPS, UMR 152, Lab Pharmacochim Subst Nat & Pharmacophores Redox, F-31062 Toulouse 9, France, Email: Genevieve.bourdy@ird.fr | ||||
| Corporate Author | Thesis | ||||
| Publisher | ELSEVIER IRELAND LTD | Place of Publication | Editor | ||
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0378-8741 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | ISI:000271790800020 | Approved | no | ||
| Call Number | EcoFoG @ eric.marcon @ | Serial | 95 | ||
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| Author | Bertani, S.; Houel, E.; Bourdy, G.; Stien, D.; Jullian, V.; Landau, I.; Deharo, E. | ||||
| Title | Quassia amara L. (Simaroubaceae) leaf tea: Effect of the growing stage and desiccation status on the antimalarial activity of a traditional preparation | Type | Journal Article | ||
| Year | 2007 | Publication | Journal of Ethnopharmacology | Abbreviated Journal |
J. Ethnopharmacol. |
| Volume | 111 | Issue | 1 | Pages | 40-42 |
| Keywords | antimalarial; Quassia amara; quassinoids; simalikalactone D; traditional medicine | ||||
| Abstract | In French Guiana, Quassia amara L. (Simaroubaceae) leaf tea is a well-known widely used traditional antimalarial remedy. Impact of the vegetal sampling condition on in vivo and in vitro antimalarial activity was assessed. Traditional infusions were prepared with juvenile or mature leaves, both either fresh or dried. Results showed that growing stage and freshness of vegetal material exert a striking effect on antimalarial activity, both in vitro and in vivo. By far, leaf tea made from fresh juvenile (FJ) Quassia amara leaves was the most active. In vitro, active component (simalikalactone D) concentration correlates biological activities, although unexplained subtle variations were observed. In vivo, tea made with dried juvenile (DJ) leaves displays a peculiar behavior, meaning that some components may help simalikalactone D delivery or may be active in vivo only, therefore enhancing the expected curative effect of the traditional preparation. (c) 2006 Elsevier Ireland Ltd. All rights reserved. | ||||
| Address | Univ Toulouse 3, Ctr IRD, UMR 152, IRD, F-97323 Cayenne Cx, Guyana, Email: eric.deharo@ird.fr | ||||
| Corporate Author | Thesis | ||||
| Publisher | ELSEVIER IRELAND LTD | Place of Publication | Editor | ||
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0378-8741 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | ISI:000246059600007 | Approved | no | ||
| Call Number | EcoFoG @ eric.marcon @ | Serial | 164 | ||
| Permanent link to this record | |||||
| Author | Odonne, G.; Bourdy, G.; Beauchene, J.; Houel, E.; Stien, D.; Chevolot, L.; Deharo, E. | ||||
| Title | From Tonic-cups to Bitter-cups: Kwasi bita beker from Suriname Determination, past and present use of an ancient galenic artefact | Type | Journal Article | ||
| Year | 2007 | Publication | Journal of Ethnopharmacology | Abbreviated Journal |
J. Ethnopharmacol. |
| Volume | 110 | Issue | 2 | Pages | 318-322 |
| Keywords | Tonic-cup; Bitter-cup; Quassia amara; Suriname; traditional remedy | ||||
| Abstract | In the main markets of Paramaribo (Suriname), many stands offer what is locally called “Bitter-cups”, or “Kwasi bita beker”, small footed-cups, roughly carved from a whitish wood. The use of these cups is strictly medicinal and it seems to be restricted to Suriname, as they are not found in neighbouring countries (Guyana, French Guiana). The aim of this study was to identify the botanical origin of Bitter-cups still in use in the Saramaka traditional medicine (as information from field people was controversial), and document the ethnopharmacology of this original galenical artefact. Microscopic and high performance liquid chromatography (HPLC) analyses were carried out on Bitter-cup, and anatomical criteria (marginal parenchyma band, size of intervessel and vessel-ray pits, rays width and rays composition, vessels clustering, frequency and size of parenchyma pits) together with HPLC profiles of the macerates showed that the wood cup was similar to Quassia amara L. (Simaroubaceae) wood. Ethnopharmacological investigation indicates that the use of these cups is simply due to the pharmacological properties attributed to “bitters”, and is strongly linked to tradition and cultural attitudes. This study also emphasizes the long lasting use of these cups, now restricted to Suriname only, with almost no variation over one century. (c) 2006 Elsevier Ireland Ltd. All rights reserved. | ||||
| Address | Univ Toulouse 3, Ctr IRD, UMR 152, F-97323 Cayenne, France, Email: genevieve.bourdy@ird.fr | ||||
| Corporate Author | Thesis | ||||
| Publisher | ELSEVIER IRELAND LTD | Place of Publication | Editor | ||
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0378-8741 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | ISI:000245486900012 | Approved | no | ||
| Call Number | EcoFoG @ eric.marcon @ | Serial | 166 | ||
| Permanent link to this record | |||||
| Author | Bertani, S.; Houel, E.; Stien, D.; Chevolot, L.; Jullian, V.; Garavito, G.; Bourdy, G.; Deharo, E. | ||||
| Title | Simalikalactone D is responsible for the antimalarial properties of an amazonian traditional remedy made with Quassia amara L. (Simaroubaceae) | Type | Journal Article | ||
| Year | 2006 | Publication | Journal of Ethnopharmacology | Abbreviated Journal |
J. Ethnopharmacol. |
| Volume | 108 | Issue | 1 | Pages | 155-157 |
| Keywords | antimalarial; Quassia amara; quassinoids; simalikalactone D; traditional medicine | ||||
| Abstract | French Guiana (North-East Amazonia) records high malaria incidence rates. The traditional antimalarial remedy most widespread there is a simple tea made out from Quassia amara L. leaves (Simaroubaceae). This herbal tea displays an excellent antimalarial activity both in vitro and in vivo. A known quassinoid, simalikalactone D (SkD), was identified as the active compound, with an IC50 value of 10 nM against FeB1 Plasmodium falciparum chloroquine resistant strain in vitro. Lastly, it inhibits 50% of Plasmodium yoelii yoelii rodent malaria parasite at 3.7 mg/kg/day in vivo by oral route. These findings confirm the traditional use of this herbal tea. (c) 2006 Elsevier Ireland Ltd. All rights reserved. | ||||
| Address | Univ Toulouse 3, UMR 152, Ctr IRD, F-97323 Cayenne, French Guiana, Email: deharo@cayenne.ird.fr | ||||
| Corporate Author | Thesis | ||||
| Publisher | ELSEVIER IRELAND LTD | Place of Publication | Editor | ||
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0378-8741 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | ISI:000241573000023 | Approved | no | ||
| Call Number | EcoFoG @ eric.marcon @ | Serial | 173 | ||
| Permanent link to this record | |||||