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Author  |
Nirma, C.; Eparvier, V.; Stien, D. |
| Title |
Reactivation of antibiosis in the entomogenous fungus Chrysoporthe sp. SNB-CN74 |
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Journal Article |
| Year |
2015 |
Publication |
Journal of Antibiotics |
Abbreviated Journal |
Journal of Antibiotics |
| Volume |
68 |
Issue |
9 |
Pages |
586-590 |
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| Abstract |
Chrysoporthe sp. SNB-CN74 was isolated from a Nasutitermes corniger nest, and its ethyl acetate extract was found to exhibit very strong antibacterial activity. Two antibacterial metabolites were isolated, (-)-R-skyrin (2) and (+)-rugulosin A (3). Eventually, the fungus lost its antibiotic potential when subcultured, and the use of yeast extract induced the re-expression of these two antibiotics. Yeast extract possibly activated a cryptic pathway by mimicking the presence of an ecological competitor. © 2015 Japan Antibiotics Research Association All rights reserved. |
| Address |
Sorbonne Universités, Laboratoire de Biodiversité et Biotechnologies Microbiennes (LBBM), Observatoire Océanologique, Banyuls-sur-mer, France |
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| Notes |
Export Date: 12 October 2015 |
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EcoFoG @ webmaster @ |
Serial |
628 |
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