Record |
Author |
Marti, G.; Eparvier, V.; Litaudon, M.; Grellier, P.; Gueritte, F. |
Title |
A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds |
Type |
Journal Article |
Year |
2010 |
Publication |
Molecules |
Abbreviated Journal |
Molecules |
Volume |
15 |
Issue |
10 |
Pages |
7106-7114 |
Keywords |
Rheedia acuminata, Clusiaceae; xanthones; antiplasmodial activity; cytotoxicity |
Abstract |
Bioassay-guided fractionation of the ethyl acetate bark extract of Rheedia acuminata led to the isolation of the new compound 1,5,6-trihydroxy-3-methoxy-7-geranyl-xanthone (1), together with four known compounds 2-5. These compounds were tested in vitro for their antiplasmodial activity on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) and for their cytotoxicity against the human diploid embryonic lung cell line MRC-5. |
Address |
[Eparvier, Veronique] CNRS, UPS2561, F-97300 Cayenne, France, Email: guillaume.marti@icsn.cnrs-gif.fr |
Corporate Author |
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Thesis |
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Publisher |
MDPI AG |
Place of Publication |
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Editor |
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Language |
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Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1420-3049 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000283587400030 |
Approved |
no |
Call Number |
EcoFoG @ webmaster @ |
Serial |
282 |
Permanent link to this record |