PT Journal
AU Touré, S
   Nirma, C
   Falkowski, M
   Dusfour, I
   Boulogne, I
   Jahn-Oyac, A
   Coke, M
   Azam, D
   Girod, R
   Moriou, C
   Odonne, G
   Stien, D
   Houel, E
   Eparvier, V
TI Aedes aegypti Larvicidal Sesquiterpene Alkaloids from Maytenus oblongata
SO Journal of Natural Products
JI Journal of Natural Products
PY 2017
BP 384
EP 390
VL 80
IS 2
AB Four new sesquiterpene alkaloids (1-4) with a β-dihydroagrofuran skeleton and a new triterpenoid (5) were isolated from an ethyl acetate extract of Maytenus oblongata stems. Their structures were elucidated using 1D and 2D NMR spectroscopy as well as MS and ECD experiments. The M. oblongata stem EtOAc extract and the pure compounds isolated were tested for larvicidal activity against Aedes aegypti under laboratory conditions, and compounds 2 and 3 were found to be active. © 2017 The American Chemical Society and American Society of Pharmacognosy.
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