TY - JOUR AU - Nirma, C. AU - Eparvier, V. AU - Stien, D. PY - 2015// TI - Reactivation of antibiosis in the entomogenous fungus Chrysoporthe sp. SNB-CN74 T2 - Journal of Antibiotics JO - Journal of Antibiotics SP - 586 EP - 590 VL - 68 IS - 9 N2 - Chrysoporthe sp. SNB-CN74 was isolated from a Nasutitermes corniger nest, and its ethyl acetate extract was found to exhibit very strong antibacterial activity. Two antibacterial metabolites were isolated, (-)-R-skyrin (2) and (+)-rugulosin A (3). Eventually, the fungus lost its antibiotic potential when subcultured, and the use of yeast extract induced the re-expression of these two antibiotics. Yeast extract possibly activated a cryptic pathway by mimicking the presence of an ecological competitor. © 2015 Japan Antibiotics Research Association All rights reserved. UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84942573894&partnerID=40&md5=2ad08cc93f6ee53820ea1e022d3af798 N1 - Export Date: 12 October 2015 ID - Nirma_etal2015 ER -