@Article{Nirma_etal2013, author="Nirma, C. and Eparvier, V. and Stien, D.", title="Antifungal agents from Pseudallescheria boydii SNB-CN73 isolated from a nasutitermes sp. termite", journal="Journal of Natural Products", year="2013", volume="76", number="5", pages="988--991", abstract="Defense mutualisms between social insects and microorganisms have been described in the literature. The present article describes the discovery of a Pseudallescheria boydii strain isolated from Nasutitermes sp. The microbial symbiont produces two antifungal metabolites: tyroscherin and N-methyltyroscherin, a compound not previously described in the literature. Methylation of tyroscherin has confirmed the structure of N-methyltyroscherin. Both compounds are effective antifungal agents with favorable selectivity indices for Candida albicans and Trichophyton rubrum. {\textcopyright} 2013 The American Chemical Society and American Society of Pharmacognosy.", optnote="Export Date: 6 June 2013; Source: Scopus; Coden: Jnprd; :doi 10.1021/np4001703; Language of Original Document: English; Correspondence Address: Eparvier, V.; CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 1 Avenue de la Terrasse, 91198 Gif-sur-Yvette, France; email: veronique.eparvier@icsn.cnrs-gif.fr", optnote="exported from refbase (http://php.ecofog.gf/refbase/show.php?record=491), last updated on Thu, 06 Jun 2013 08:16:45 -0300", issn="01633864 (Issn)", opturl="http://www.scopus.com/inward/record.url?eid=2-s2.0-84878224354&partnerID=40&md5=3cdeb9ae06ce6645d6835533e1a64e29" }