TY  - JOUR
AU  - Basset, C.
AU  - Rodrigues, A.M.S.
AU  - Eparvier, V.
AU  - Silva, M.R.R.
AU  - Lopes, N.P.
AU  - Sabatier, D.
AU  - Fonty, E.
AU  - Espindola, L.S.
AU  - Stien, D.
PY  - 2012//
TI  - Secondary metabolites from Spirotropis longifolia (DC) Baill and their antifungal activity against human pathogenic fungi
T2  - Phytochemistry
JO  - Phytochemistry
SP  - 166
EP  - 172
VL  - 74
KW  - Antifungal
KW  - Cytotoxic
KW  - Leguminosae
KW  - Monodominant species
KW  - Prenylated pterocarpans
KW  - Spirotropis longifolia
N2  - A phytochemical study of the ethyl acetate extract of the roots and adventitious roots of Spirotropis longifolia, a monodominant tree species of the Guianan rainforest, has allowed the isolation of three compounds: 2-hydroxy-8,9-methylenedioxy-2′,2′-dimethylpyrano-[5′, 6′:4,3]-6a-prenyl-[6aS,11aS]-pterocarpan (spirotropin A), 2-hydroxy-8,9-methylenedioxy-2′,2′-dimethyl-3′, 4′-dihydropyrano-[5′,6′:4,3]-6a-prenyl-[6aS,11aS]-pterocarpan (spirotropin B), and 5,7-dihydroxy-6,8-diprenyl-2,2-dimethylpyrano[5,6: 3′,4′]-isoflavone (spirotropone). In addition, 10 known compounds, trans-oxyresveratrol, trans-resveratrol, piceatannol, daidzein, genistein, isoprunetin, lupeol, latifolol, gnetin D and gnetin E, were also isolated. These compounds were evaluated for their antifungal activity and their cytotoxicity, and their structures were established by 1D and 2D NMR, HRMS, CD and optical rotation measurements. © 2011 Elsevier Ltd. All rights reserved.
SN  - 00319422 (Issn)
UR  - http://www.scopus.com/inward/record.url?eid=2-s2.0-84855970553&partnerID=40&md5=26aeec8f92041c34bd59d87c53eb73b4
N1  - Export Date: 23 February 2012; Source: Scopus; Coden: Pytca; doi: 10.1016/j.phytochem.2011.10.011; Language of Original Document: English; Correspondence Address: Espindola, L.S.; Laboratório de Farmacognosia, Universidade de Brasília, Brasília, DF, Brazil; email: darvenne@unb.br
ID  - Basset_etal2012
ER  -