%0 Journal Article
%T Secondary metabolites from Spirotropis longifolia (DC) Baill and their antifungal activity against human pathogenic fungi
%A Basset, C.
%A Rodrigues, A.M.S.
%A Eparvier, V.
%A Silva, M.R.R.
%A Lopes, N.P.
%A Sabatier, D.
%A Fonty, E.
%A Espindola, L.S.
%A Stien, D.
%J Phytochemistry
%D 2012
%V 74
%@ 00319422 (Issn)
%F Basset_etal2012
%O Export Date: 23 February 2012; Source: Scopus; Coden: Pytca; doi: 10.1016/j.phytochem.2011.10.011; Language of Original Document: English; Correspondence Address: Espindola, L.S.; Laboratório de Farmacognosia, Universidade de Brasília, Brasília, DF, Brazil; email: darvenne@unb.br
%O exported from refbase (http://php.ecofog.gf/refbase/show.php?record=381), last updated on Thu, 23 Feb 2012 08:05:55 -0300
%X A phytochemical study of the ethyl acetate extract of the roots and adventitious roots of Spirotropis longifolia, a monodominant tree species of the Guianan rainforest, has allowed the isolation of three compounds: 2-hydroxy-8,9-methylenedioxy-2′,2′-dimethylpyrano-[5′, 6′:4,3]-6a-prenyl-[6aS,11aS]-pterocarpan (spirotropin A), 2-hydroxy-8,9-methylenedioxy-2′,2′-dimethyl-3′, 4′-dihydropyrano-[5′,6′:4,3]-6a-prenyl-[6aS,11aS]-pterocarpan (spirotropin B), and 5,7-dihydroxy-6,8-diprenyl-2,2-dimethylpyrano[5,6: 3′,4′]-isoflavone (spirotropone). In addition, 10 known compounds, trans-oxyresveratrol, trans-resveratrol, piceatannol, daidzein, genistein, isoprunetin, lupeol, latifolol, gnetin D and gnetin E, were also isolated. These compounds were evaluated for their antifungal activity and their cytotoxicity, and their structures were established by 1D and 2D NMR, HRMS, CD and optical rotation measurements. © 2011 Elsevier Ltd. All rights reserved.
%K Antifungal
%K Cytotoxic
%K Leguminosae
%K Monodominant species
%K Prenylated pterocarpans
%K Spirotropis longifolia
%U http://www.scopus.com/inward/record.url?eid=2-s2.0-84855970553&partnerID=40&md5=26aeec8f92041c34bd59d87c53eb73b4
%P 166-172