@Article{Basset_etal2012, author="Basset, C. and Rodrigues, A.M.S. and Eparvier, V. and Silva, M.R.R. and Lopes, N.P. and Sabatier, D. and Fonty, E. and Espindola, L.S. and Stien, D.", title="Secondary metabolites from Spirotropis longifolia (DC) Baill and their antifungal activity against human pathogenic fungi", journal="Phytochemistry", year="2012", volume="74", pages="166--172", optkeywords="Antifungal", optkeywords="Cytotoxic", optkeywords="Leguminosae", optkeywords="Monodominant species", optkeywords="Prenylated pterocarpans", optkeywords="Spirotropis longifolia", abstract="A phytochemical study of the ethyl acetate extract of the roots and adventitious roots of Spirotropis longifolia, a monodominant tree species of the Guianan rainforest, has allowed the isolation of three compounds: 2-hydroxy-8,9-methylenedioxy-2{\textasciiacutex},2{\textasciiacutex}-dimethylpyrano-[5{\textasciiacutex}, 6{\textasciiacutex}:4,3]-6a-prenyl-[6aS,11aS]-pterocarpan (spirotropin A), 2-hydroxy-8,9-methylenedioxy-2{\textasciiacutex},2{\textasciiacutex}-dimethyl-3{\textasciiacutex}, 4{\textasciiacutex}-dihydropyrano-[5{\textasciiacutex},6{\textasciiacutex}:4,3]-6a-prenyl-[6aS,11aS]-pterocarpan (spirotropin B), and 5,7-dihydroxy-6,8-diprenyl-2,2-dimethylpyrano[5,6: 3{\textasciiacutex},4{\textasciiacutex}]-isoflavone (spirotropone). In addition, 10 known compounds, trans-oxyresveratrol, trans-resveratrol, piceatannol, daidzein, genistein, isoprunetin, lupeol, latifolol, gnetin D and gnetin E, were also isolated. These compounds were evaluated for their antifungal activity and their cytotoxicity, and their structures were established by 1D and 2D NMR, HRMS, CD and optical rotation measurements. {\textcopyright} 2011 Elsevier Ltd. All rights reserved.", optnote="Export Date: 23 February 2012; Source: Scopus; Coden: Pytca; doi: 10.1016/j.phytochem.2011.10.011; Language of Original Document: English; Correspondence Address: Espindola, L.S.; Laborat{\'o}rio de Farmacognosia, Universidade de Bras{\'i}lia, Bras{\'i}lia, DF, Brazil; email: darvenne@unb.br", optnote="exported from refbase (http://php.ecofog.gf/refbase/show.php?record=381), last updated on Thu, 23 Feb 2012 08:05:55 -0300", issn="00319422 (Issn)", opturl="http://www.scopus.com/inward/record.url?eid=2-s2.0-84855970553&partnerID=40&md5=26aeec8f92041c34bd59d87c53eb73b4" }