TY  - JOUR
AU  - Marti, G.
AU  - Eparvier, V.
AU  - Litaudon, M.
AU  - Grellier, P.
AU  - Gueritte, F.
PY  - 2010//
TI  - A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds
T2  - Molecules
JO  - Molecules
SP  - 7106
EP  - 7114
VL  - 15
IS  - 10
PB  - MDPI AG
KW  - Rheedia acuminata
KW  - Clusiaceae
KW  - xanthones
KW  - antiplasmodial activity
KW  - cytotoxicity
N2  - Bioassay-guided fractionation of the ethyl acetate bark extract of Rheedia acuminata led to the isolation of the new compound 1,5,6-trihydroxy-3-methoxy-7-geranyl-xanthone (1), together with four known compounds 2-5. These compounds were tested in vitro for their antiplasmodial activity on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) and for their cytotoxicity against the human diploid embryonic lung cell line MRC-5.
SN  - 1420-3049
N1  - ISI:000283587400030
ID  - Marti_etal2010
ER  -