%0 Journal Article
%T A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds
%A Marti, G.
%A Eparvier, V.
%A Litaudon, M.
%A Grellier, P.
%A Gueritte, F.
%J Molecules
%D 2010
%V 15
%N 10
%I MDPI AG
%@ 1420-3049
%F Marti_etal2010
%O ISI:000283587400030
%O exported from refbase (http://php.ecofog.gf/refbase/show.php?record=282), last updated on Wed, 04 May 2011 12:17:12 -0300
%X Bioassay-guided fractionation of the ethyl acetate bark extract of Rheedia acuminata led to the isolation of the new compound 1,5,6-trihydroxy-3-methoxy-7-geranyl-xanthone (1), together with four known compounds 2-5. These compounds were tested in vitro for their antiplasmodial activity on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) and for their cytotoxicity against the human diploid embryonic lung cell line MRC-5.
%K Rheedia acuminata
%K Clusiaceae
%K xanthones
%K antiplasmodial activity
%K cytotoxicity
%P 7106-7114