TY - JOUR AU - Rodrigues, A.M.S. AU - Theodoro, P.N.E.T. AU - Eparvier, V. AU - Basset, C. AU - Silva, M.R.R. AU - Beauchene, J. AU - Espindola, L.S. AU - Stien, D. PY - 2010// TI - Search for Antifungal Compounds from the Wood of Durable Tropical Trees T2 - J. Nat. Prod. JO - Journal of Natural Products SP - 1706 EP - 1707 VL - 73 IS - 10 PB - AMER CHEMICAL SOC N2 - Research on antifungal compounds from the durable wood from French Guiana Amazonian forest trees highlights the correlation between the activity of their extracts against wood-rotting fungi and human pathogens. The fractionation of an ethyl acetate extract of Sextonia rubra wood led to the isolation of rubrenolide (1) and rubrynolide (2). The potential of compounds 1 and 2 is described through the evaluation of their activity against 16 pathogenic fungi and their cytotoxicity toward NIH-3T3 mammalian fibroblast cells. SN - 0163-3864 N1 - ISI:000283288900015 ID - Rodrigues_etal2010 ER -