PT Journal
AU Rodrigues, A
   Theodoro, P
   Eparvier, V
   Basset, C
   Silva, M
   Beauchene, J
   Espindola, L
   Stien, D
TI Search for Antifungal Compounds from the Wood of Durable Tropical Trees
SO Journal of Natural Products
JI J. Nat. Prod.
PY 2010
BP 1706
EP 1707
VL 73
IS 10
AB Research on antifungal compounds from the durable wood from French Guiana Amazonian forest trees highlights the correlation between the activity of their extracts against wood-rotting fungi and human pathogens. The fractionation of an ethyl acetate extract of Sextonia rubra wood led to the isolation of rubrenolide (1) and rubrynolide (2). The potential of compounds 1 and 2 is described through the evaluation of their activity against 16 pathogenic fungi and their cytotoxicity toward NIH-3T3 mammalian fibroblast cells.
ER