%0 Journal Article
%T Reactivation of antibiosis in the entomogenous fungus Chrysoporthe sp. SNB-CN74
%A Nirma, C.
%A Eparvier, V.
%A Stien, D.
%J Journal of Antibiotics
%D 2015
%V 68
%N 9
%F Nirma_etal2015
%O Export Date: 12 October 2015
%O exported from refbase (http://php.ecofog.gf/refbase/show.php?record=628), last updated on Mon, 12 Oct 2015 10:39:47 -0300
%X Chrysoporthe sp. SNB-CN74 was isolated from a Nasutitermes corniger nest, and its ethyl acetate extract was found to exhibit very strong antibacterial activity. Two antibacterial metabolites were isolated, (-)-R-skyrin (2) and (+)-rugulosin A (3). Eventually, the fungus lost its antibiotic potential when subcultured, and the use of yeast extract induced the re-expression of these two antibiotics. Yeast extract possibly activated a cryptic pathway by mimicking the presence of an ecological competitor. © 2015 Japan Antibiotics Research Association All rights reserved.
%U http://www.scopus.com/inward/record.url?eid=2-s2.0-84942573894&partnerID=40&md5=2ad08cc93f6ee53820ea1e022d3af798
%P 586-590