@Article{Cachet_etal2012,
author="Cachet, N.
and Ho-A-Kwie, F.
and Rivaud, M.
and Houel, E.
and Deharo, E.
and Bourdy, G.
and Jullian, V.",
title="Picrasin K, a new quassinoid from Quassia amara L. (Simaroubaceae)",
journal="Phytochemistry Letters",
year="2012",
volume="5",
number="1",
pages="162--164",
optkeywords="Malaria",
optkeywords="P. falciparum",
optkeywords="Quassia amara",
optkeywords="Quassinoids",
optkeywords="Simaroubaceae",
abstract="A new quassinoid Picrasin K 1 was isolated from a decoction made of Quassia amara leaves, traditionally used in French Guyana to treat malaria. The structure and relative stereochemistry of 1 was determined through extensive NMR analysis. Picrasin K showed a low activity against Plasmodium falciparum in vitro (IC 50 = 8 $\mu$M), and a similar low activity on human cancerous cells line (IC 50 = 7 $\mu$M on MCF-7 cells line). {\textcopyright} 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.",
optnote="Export Date: 8 March 2012; Source: Scopus; doi: 10.1016/j.phytol.2011.12.001; Language of Original Document: English; Correspondence Address: Jullian, V.; UMR-152 Pharma-Dev, IRD, Universit{\'e} Paul Sabatier Toulouse 3, 31062 Toulouse, France; email: jullian@cict.fr",
optnote="exported from refbase (http://php.ecofog.gf/refbase/show.php?record=382), last updated on Mon, 21 Jan 2013 11:39:48 -0300",
issn="18743900 (Issn)",
opturl="http://www.scopus.com/inward/record.url?eid=2-s2.0-84856701045&partnerID=40&md5=ec6ef03134af95b40652427eb15acba9"
}