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Author Dejean, Alain openurl 
  Title Ant-Plant Interactions: Impacts of Humans on Terrestrial Ecosystems edited by Paulo S. Oliveira and Suzanne Koptur Type Journal Article
  Year 2018 Publication The Quarterly Review Of Biology Abbreviated Journal  
  Volume 93 Issue 2 Pages 138-139  
  Keywords  
  Abstract (down) Revue de l'ouvrage : Edited by Paulo S. Oliveira and Suzanne Koptur.
Cambridge and New York: Cambridge University Press.
$84.99. xix + 431 p. + 8 pl.; ill.; index. ISBN: 978-
1-107-15975-4. 2017.
 
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  Notes Approved no  
  Call Number EcoFoG @ webmaster @ Serial 316  
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Author Houël, Emeline; Stien, Didier; Bourdy, Geneviève; Deharo, Eric doi  openurl
  Title Chapter 161: Quassinoids: anticancer and antimalarial activities Type Book Chapter
  Year 2013 Publication Handbook of Natural Products Abbreviated Journal  
  Volume Issue Pages 3775 - 3802  
  Keywords  
  Abstract (down) Quassinoids were initially isolated as bitter principles of plants of the Simaroubaceae family. These natural products are formed by oxidative degradation of triterpene derivatives. Since the 1970s, these molecules have attracted attention because of their promising biological activities, especially in the context of research regarding active anticancer and antimalarial principles. In this chapter, the structural diversity of quassinoids and their botanical and geographical occurrence are described, combining a historical perspective from the literature references regarding these two major biological activities and focusing on the results obtained in vivo with the most promising compounds; in vitro studies are less relevant and have already been extensively reviewed in the literature. The biological activities with respect to the uses of the corresponding Simaroubaceae in traditional medicine are also analyzed.  
  Address  
  Corporate Author Thesis  
  Publisher Springer-Verlag Place of Publication Berlin Heidelberg Editor Ramawat, Kishan Gopal; Merillon, Jean-Michel  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
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  Area Expedition Conference  
  Notes Approved no  
  Call Number EcoFoG @ webmaster @ Serial 164  
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Author Houël, E.; Fleury, M.; Jullian, V.; Vonthron-Sénécheau, C.; Nardella, F.; Villa, P.; Odonne, G.; Eparvier, V.; Deharo, E.; Stien, D. doi  openurl
  Title TakamalaImë (Psidium acutangulum Mart ex. DC): Understanding the use of an antimalarial traditional remedy from French Guiana Type Journal Article
  Year 2014 Publication Planta Medica Abbreviated Journal Planta Med  
  Volume 80 Issue 10 Pages Pd90  
  Keywords  
  Abstract (down) Psidium acutangulum Mart. ex DC is used exclusively by the Wayana Amerindians in French Guiana, more particularly for the treatment of malaria. To understand this specific use, we embarked upon evaluating the antimalarial and anti-inflammatory activities of this traditional remedy as prepared by the Amerindian users. The decoction exerted good antiplasmodial activity in vitro (IC50 4 µg/ml on P. falciparum FcB1) and in vivo (39.7% inhibition of P. berghei NK65 in the murine model at 2 × 150 µl/day), as well as a strong anti-inflammatory effect in vitro regarding IL-1β, IL-6 and IL-8. Fractionation of the ethyl acetate extract (IC50 < 1 µg/ml) led to the isolation of six pure compounds, two of them, guaijaverine and the new compound wayanine, being moderately active against P. falciparum FcB1 in vitro (IC50 5 – 7 µg/ml). Along with the absence of cytotoxicity of the decoction and pure compounds, these results support the traditional use of this plant.  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0032-0943 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number EcoFoG @ webmaster @ Serial 233  
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Author Rodrigues, A.; Theodoro, P.; Basset, C.; Espindola, L.; Stien, D. doi  openurl
  Title Bio-inspiration in the discovery of active natural products: an example with the search of antifungal agents inspired from long-lasting woods Type Conference Article
  Year 2010 Publication Planta Medica Abbreviated Journal Planta Med.  
  Volume 76 Issue 12 Pages 1293  
  Keywords  
  Abstract (down) Plant natural products have been perfected through evolution with respect to their specific biological roles (defense, elicitor, and so on) and are, therefore, an excellent starting point in the search for new biologically active chemicals. Hence, despite the progressive abandonment of the exploration of naturally sourced bioactive substances by the pharmaceutical industry, more than half of the drugs approved in the United States between 2005 and 2007 are natural products or natural product-derived drugs, five of which constituted the first members of new drug classes [1]. Clearly, chemical research into natural substances still has an important role to play in improving quality of life, and can play an important role by inventing innovative strategies to discover new bioactive compounds [1,2].

In the present work, we demonstrated that a bio-inspired approach for the identification of novel bioactive natural products represents a promising biotechnological tool for the development of new drugs. We have studied how natural defenses within decay-resistant wood can generate a large number of positive hits in the search for antimycotic agents. In addition, it was found from bioguided fractionation that ethyl acetate extracts of Sextonia rubra wood contain a relatively large proportion of antifungal metabolites rubrenolide (1) and rubrynolide (2), 1 being slightly more active than 2. The therapeutic potential of the above compounds will be discussed through the evaluation of their antifungal activities against 16 pathogenic fungi strains and their cytotoxicities towards KB cells.
 
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  Area Expedition Conference 58th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Berlin, Germany, 29th August - 2nd September 2010  
  Notes Approved no  
  Call Number EcoFoG @ webmaster @ Serial 181  
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Author Basset, C.; Stien, D.; Espindola, S.L. doi  openurl
  Title Research of antifungal compounds from the Amazonian biomass by a bio-inspired approach Type Conference Article
  Year 2010 Publication Planta Medica Abbreviated Journal Planta Med.  
  Volume 76 Issue 12 Pages 1172  
  Keywords  
  Abstract (down) Our research aims at understanding the chemical resistance mechanisms of durable woods against fungi. Our ultimate goal is to isolate and identify antifungal compounds from these woods that could be used for the treatment of human fungal diseases. We therefore screened highly durable Amazonian wood selected from technical databases [1] and demonstrated that bioactive secondary metabolites responsible of the natural durability of the woods [2] can also be used to treat mycoses. This screening has given a very high ...  
  Address Basset, C.] UAG, UMR ECOFOG, Cayenne 97337, French Guiana  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0032-0943 ISBN Medium  
  Area Expedition Conference 58th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Berlin, Germany, 29th August - 2nd September 2010  
  Notes ISI:000282066500035 Approved no  
  Call Number EcoFoG @ webmaster @ Serial 183  
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Author Brechet, L. pdf  openurl
  Title Composition chimique et resorption foliaire chez 21 espèces d'arbres tropicaux Type Thesis
  Year 2004 Publication Abbreviated Journal  
  Volume Issue Pages 31  
  Keywords Foret Tropicale Humide; Arbres; Composition Chimique Des Feuilles; Efficience De Resorption Des Nutriments; Qualite De La Litiere  
  Abstract (down) Nous avons analysé la composition chimique de feuilles matures et sénescentes de 21 espèces d'arbres de forêt tropicale humide. Ces arbres ont été plantés il y a 20 ans, sur un sol unifonl1e pour tous, sous forme de jeunes plants. Cette plantation est organisée sous fonne de placeaux monospécifïques et est située près de Kourou, en Guyane française. Les mesures de concentration d'azote, de phosphore, de carbone et des polyphénols ont été réalisées et ont permis de calculer le rapport C/N et la résorption des nutriments. Les compositions chimiques varient radicalement entre les espèces à la fois pour les feuilles matures et sénescentes: dans les feuilles matures les concentration en N et P varient de 1,03% à 2,69% et de 0,037% à 0,115%, respectivement. La concentration d'N dans les feuilles sénescentes varie de 0,72% à 2,03% et pour le P de 0,013% à 0.074%. La vitesse de croissance est positivement corrélée avec la concentration d'N dans les feuilles. La résorption est le phénomène suivant lequel les plantes ré-absorbent les nutriments des feuilles avant la période d'abscission pour les re-distribuer à travers ses tissus. L'efficience de résorption varie fortement en fonction des espèces et est plus élevée pour le P que pour I"N. La résorption de l'N varie de -9,84% à 57,22% (moyenne=30,7%) el celle du P varie de -15,75% il 79,56% (moyenne~47,64%). Une analyse par corrélation montre que les résorptions de N et P sont significativement et positivement corrélés. Il y a aussi une corrélation significative et positive entre l'efficience de résorption et i) les concentrations en nutriment dans les feuilles vel1es et ii) le coflt de construction des feuilles et la vitesse de croissance. Parmi les espèces, une fone relation positive est trouvée entre le C/N de la litière et la résorption de l'N, suggérant que celle-ci est un élément déteminant de la qualité de la litière. Une fl)rte résorption entraîne une faible qualité de litière el par conséquent une mauvaise décomposition. La résorption et la décomposition. sont liés dans le recyclage des nutriments dans les écosystèmes. et sont négativement corrélés. Il semble que la connaissance de la résorption seule ou de la décomposition seule peut fausser la compréhension du fonctionnement de l'écosystème ou des espèces.  
  Address  
  Corporate Author Thesis Diploma thesis  
  Publisher Université de Poitiers Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Roy, J.; Hattenschwiller, S. Series Title Abbreviated Series Title U.F.R. Sciences Fondamentales et Appliquées  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number EcoFoG @ webmaster @ 169 Serial 48  
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Author Marcon, Eric pdf  openurl
  Title Mesurer la Biodiversité et la Structuration Spatiale Type Thesis
  Year 2016 Publication Abbreviated Journal  
  Volume Issue Pages 321  
  Keywords Statisitques spatiales; Processus ponctuels; Biodiversité;Entropie  
  Abstract (down) Mes travaux de recherche portent sur la caractérisation de l’hétérogénéité, précisément des structures spatiales et de la diversité. J’ai développé de nouvelles mesures de la structure spatiale appliquées principalement en économie géographique et des mesures de diversité appliquées principalement à la biodiversité des arbres. Le fil directeur de ces travaux méthodologiques est de construire des mesures correspondant à une réalité physique, facilement compréhensible, pouvant être utilisées ensuite pour comprendre sans ambiguïté les processus économiques ou écologiques concernés.

Mon projet de recherche à moyen terme consiste à combiner les deux approches pour caractériser la diversité explicitement dans l’espace et dans le temps, et à étendre mes méthodes à d’autres objets (diversité microbienne par exemple) plus complexes. Au-delà de ces travaux méthodologiques, mon objectif à plus long terme est d’aller vers la modélisation des processus générant les patrons de diversité.
 
  Address  
  Corporate Author Thesis Habilitation thesis  
  Publisher Université de Guyane Place of Publication Kourou - Guyane française Editor  
  Language Francais Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number EcoFoG @ webmaster @ Serial 262  
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Author Fu, T. ; Touboul, D. ; Della-Negra, S. ; Houël, E. ; Amusant, N. ; Duplais, C. ; Brunelle, A. openurl 
  Title Localization od bioactive metabolites in durable ? Tropical tree Sextonia rubra (Lauracaea) with argon and bismuth cluster dual beam depth profiliing and imaging Type Conference Article
  Year 2016 Publication Imaging mass spectrometry conference – Ustron – Pologne – Octobre 2016 Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract (down) Many tropical tree species generate natural decay resistance by producing bioactive metabolites. Among them, Sextonia rubra (Lauraceae) is a widely exploited species for construction in French Guiana. Rubrynolide and rubrenolide, which are secondary metabolites isolated from the stem wood of S. rubra, exhibit potent antifungal and termiticidal activities that result in the exceptional durability of the heartwood. Although the structure and total synthesis of these two biologically active compounds have been well described in literature, little is known about their cellular localization or biosynthesis process in living trees. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has been well known for its high lateral resolution imaging with a typical beam size of 0.4-2 µm, thus sufficient to image the wood surface at subcellular level.
Wood surfaces of sapwood, transition zone and heartwood from living trees of S. rubra were prepared with ultramicrotome using diamond knife. Each surface was mapped by Bi3+ cluster TOF-SIMS with high lateral resolution (~ 0.4 µm) which was achieved by employing burst alignment primary ion focusing mode with an extraction delay of the secondary ions to improve mass resolution. 3D imaging of a multi-structure wood sample was performed using dual beam depth profiling method, with 25 keV Bi3+ and 10 keV Ar1000+ as analysis and sputter beam, respectively. To examine the effect of life-history traits on the production of bioactive metabolites, the corresponding counterparts from a tree which had suffered stress during growth were investigated as well.
 
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  Notes Approved no  
  Call Number EcoFoG @ carole.legrand @ Serial 302  
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Author Nirma, C.; Rodrigues, A.; Basset, C.; Stien, D.; Eparvier, V. doi  openurl
  Title Isoflavonoids with insecticide and larvicide activities from Muellera frutescens Standl Type Conference Article
  Year 2010 Publication Planta Medica Abbreviated Journal Planta Med.  
  Volume 76 Issue 12 Pages 1197-1198  
  Keywords  
  Abstract (down) Many plants of the Fabaceae family, are used as fish poisoning and insecticides [1,2]. The genus Muellera in this family is represented by only seven species of climbers and trees and is distributed over south and central America. In 1984, Geesink proposed to consider Muellera as Lonchocarpus synonymous [3]. The Lonchocarpus genera is well known in French Guiana because of its traditional utilization as a fish poisoning [4]. However, one study only reported ethnobotanical use of M. frutescens as an ichtyotoxic plant. Furthermore, no ethnopharmacological use or biological activity data was ever reported in the literature for this plant. Many chemical studies dealing with Lonchocarpus genera have been published [5,6,7]. Phytochemical investigation of barks, stems and rarely leaves described isolation of active isoflavonoids named rotenoids. This study aims at conducting a phytochemical survey of Muellera frutescens in order to evaluate whether or not Muellera is closely related to Lonchocarpus and eventually isolate new bioactive secondary metabolites. Three different extracts (hexane, ethyl acetate and methanol) of bark, roots and leaves were prepared and tested on various biological assays. We discovered insecticide and larvicide activities for all extracts, and none of them exhibited cytotoxicity on human cells. The bioguided fractionation of the most active extract (bark hexane extract) allowed us to isolate eight isoflavonoids, the structures of which were elucidated by spectroscopic methods. It was found that Muellera is indeed closely related to Lonchocarpus, therefore corroborating Geesink's proposal.  
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  Call Number EcoFoG @ webmaster @ Serial 178  
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Author Marcon, Eric pdf  openurl
  Title Statistiques spatiales avec applications à l’écologie et à l’économie Type Thesis
  Year 2010 Publication Abbreviated Journal  
  Volume Issue Pages 297  
  Keywords  
  Abstract (down) Les statistiques spatiales sont pour les écologues un ensemble d'outils permettant de caractériser la structure d'un semis de points, par exemple une carte représentant des emplacements des arbres dans une parcelle de forêt. Cette structure est définie implicitement comme un écart à semis complètement aléatoire, résultat d'un processus de Poisson. L'hétérogénéité du processus ponctuel dont le semis de points est une réalisation et la non-indépendance des points en sont les causes indiscernables, ce qui amène généralement à supposer l'intensité du processus connu et nommer « concentration spatiale » ou « agrégation » (la régularité spatiale est possible, mais rare en pratique) la non-indépendance. Une revue de la littérature des processus ponctuels et des mesures de structures spatiales est fournie pour clarifier les concepts et les choix.

L'objectif de ce travail de thèse était de produire des améliorations méthodologiques. Ses résultats principaux sont :
- L'établissement d'un test pour la principale statistique utilisée, la fonction K de Ripley, permettant de s'affranchir de la méthode de Monte-Carlo utilisée dans la littérature pour rejeter l'hypothèse nulle d'un processus complètement aléatoire.
- L'extension de K aux processus hétérogènes, dans le cadre d'une typologie claire des statistiques (absolues, relatives, topographiques).

Lorsque la position exacte des objets n'est pas connue, mais que des effectifs par zone sont disponibles (par exemple des nombres d'arbres par parcelle), la théorie de l'information est utilisée pour définir un cadre général permettant de caractériser la structure spatiale (des espèces dans les parcelles) et la diversité (des parcelles, en termes d'espèces) comme deux aspects d'une même mesure d'inégalité. Ce cadre est appliqué à l'indice de biodiversité de Shannon pour définir clairement la mesure de diversité bêta, son calcul direct indépendamment de la différence entre diversités gamma et alpha, et fournir un test statistique de non nullité. La voie est ouverte pour l'application à d'autres mesures de diversité et de structure spatiale.

En conclusion, il semble clair que ces outils de caractérisation sont un premier pas pour traiter les questions écologiques, leur développement étant toujours du domaine de la recherche. Ils sont cependant très insuffisants pour répondre à des questions liées aux processus écologiques, assez éloignés des processus ponctuels qui ignorent l'aspect temporel de l'installation des objets.
 
  Address  
  Corporate Author Thesis Ph.D. thesis  
  Publisher AgroParisTech Place of Publication Kourou Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number EcoFoG @ webmaster @ Serial 13  
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